Dexmedetomidine in spinal anaesthesia thesis
Dexmedetomidine in spinal anaesthesia thesis
Under proper aseptic conditions, spinal anesthesia was given at the level of L4-L5 interspace in sitting position using a midline or paramedian approach by a 25G Quincke spinal needle. In all the patients, maximum sensory level recorded at 20 min was similar to or higher than the sensory level recorded immediately post-operatively. Studies show that the use of spinal dexmedetomidine may be beneficial to improve the quality of spinal anesthesia, potentiate the analgesic efficacy, provide prolonged postoperative analgesia and lower postoperative pain scores. However, opioid-induced side effects, such as pruritus, nausea, or vomiting, could be an obstacle in common use. Similar to our findings, Ravipati [ 15 ] observed pruritus only in fentanyl group while nausea and vomiting was more common in dexmedetomidine, with no significant difference between groups. Trial registration Open Peer Review reports Background Lower limb surgeries could be performed under local, neuroaxial and general anesthesia, but neuroaxial block is the preferred method. Side effects may occur by using any anesthesia medications. Dexmedetomidine has been widely used for anesthesia and analgesic purposes. Sensory onset was faster in Group D and slowest in Group B. Highest duration of sensory blockade was seen in Group B and lowest in Group D. Figure 1: Post-operative Verbal Rating Scale scores. Vitals included HR, mean arterial pressure MAP , and SPO2 recorded at 0, 2, 5, 10, 15, 20, 25, 30, 40, 50, 60, 70, 80, and 90 min Adverse events included hypotension, bradycardia, and nausea.
Statistical analysis was done using appropriate tests. The intervention will be compared to the sole use of bupivacaine spinal anesthesia.
Methods: This study is a prospective randomised controlled double blind study. Maximum height of the block attained was recorded at 20 min from the time of subarachnoid block. After injection of drug subarachnoidpatients were made to sit for 5 min, after which patients were placed in supine position.
Dexmedetomidine as adjuvant
Statistical analysis was done using appropriate tests. Just before spinal anaesthesia, syringe was handed over to the anaesthesiologist performing the subarachnoid block, who was also the observer of the study. Group N received intrathecal 0. Our study concurs with the study conducted by Grandhe et al. Highest time was seen in Group D and lowest in Group B. Figure 2: Mean arterial pressure In our study, there was no significant variation in the SPO2 at various intervals. If appropriate, for articles located in other languages, authors will be contacted to identify if they are also published in English. Sanvi, Stephanie Abstract Review question: The current review aims to identify the effects of intrathecal dexmedetomidine as an adjuvant to bupivacaine spinal anesthesia compared to the sole use of bupivacaine spinal anesthesia alone in adult patients undergoing elective surgical procedures. Asano et al. Analgesic was administered when VRS was more than 3 and consisted of injection diclofenac 75 mg intramuscular that could be repeated after 12 h if needed with a maximum daily dose of mg. First, fentanyl compared to other opioids is less likely to cause respiratory suppression. Side effects may occur by using any anesthesia medications. This difference in adverse effects between three groups was statistically significant. Highest duration of sensory blockade was seen in Group B and lowest in Group D.
The patients received 2. The incidence of side effects was not statistically significant in both the groups [Table 3].
Moreover, time to regression to S1 sensory level and regression of two sensory levels in BD group was significantly longer than the other groups.
Iv dexmedetomidine in spinal anaesthesia
Results: Time for regression of sensory level and time for first administration of analgesic were prolonged in Group D It has been found to be a definitive adjuvant to prolong the duration of analgesia. Statistical analysis was done using appropriate tests. This study was conducted in a randomized, double-blind, controlled fashion. Our study concurs with the study conducted by Grandhe et al. However, the duration of motor blockade, time to ambulation, and time to void were also significantly prolonged in Group D Patient anxious, agitated, or restless Patient-cooperative, oriented, and tranquil alert Patient responds to commands Asleep but with brisk response to light glabellar tap or loud auditory stimulus Asleep, sluggish response to light glabellar tap or loud auditory stimulus Asleep, no response to light glabellar tap or loud auditory stimulus. Acknowledgement We acknowledge the contribution of Dr.
In the operating room, electrocardiogram, pulse oximetry and non-invasive blood pressure BP were monitored, and baseline values were recorded. After spinal block, the level of sensory block, defined as the dermatomal segment with loss of pain sensation to pin-prick with a 22 G hypodermic needle and cold sensation to alcohol swab was measured every 2 min after intrathecal injection.
based on 110 review